Evaluation of Immunodulatory effect of Stresroak Premix in Broiler Chick

Introduction adaptogenic, immunomodulatory, free radical scavenging and antioxidant rejuvenating actions Irrational use of antibiotics as growth promoter (Shukla and Srivastava, 1999). The constituent herbs and as therapeutic agent or immunomodulator in of polyherbal formulation Stresroak which are livestock and poultry is current issue. International Phyllanthus emblica, Withania Somnifera, Magnifera institutions and organizations related to public health indica, Ocimum sanctum and many more are showing deep concern to reduce the use of antibiotics scientif ical ly proved for their antistressor, in animals and poultry. This absurd use of antibiotics is immunomodulator, adaptogenic and performance not only developing an increased resistance to enhancing property (Oyagbemi et al. 2008 and antibiotics but also presence of residue in animal Manoharan, 2004). products is matter of attention for public health importance. An International Study Group on Materials and Methods Antimicrobial Strategies (ISGNAS) has also mentioned Present study was conducted at the Department the increased microbial resistance to antibiotics is a of Pharmacology & Toxicology, Bombay Veterinary serious problem. Day to day managemental practices College, Mumbai (MS) India. Chicks were procured imposes stress on broiler chick which leads to from Kanakeshwara Hatcheries, Aurangabad and decreased performance and also reflects on immunity vaccinated against ND (LaSota strain) and IBD of chicks. Different managemental stress predisposes (Georgia strain) on 6th and 14th day respectively. Four chicks to immunosuppression and exposes to hundred and fifty healthy days old chicks were infections. Withania Somnifera, Ocimum sanctum randomly divided into three groups (each group herbs is well known for its immunomodulatory property consisting of 150 chicks). Group A served as a negative as ra t iona l a l ternat ive o f ant ib io t ics for control while group B served as a positive control immunopotentiation and increasing the growth and receiving levamisole, a known immunomodulator @ 15 performance. Polyherbal formulation Stresroak (M/s mg/kg body weight through water for four consecutive Ayurvet Ltd. Baddi, India) is a scientifically proven to be days from third day onwards. Group C birds were Abstract